ReN-1869 hydrochloride

• CAT Number: I013581
• CAS Number: 170149-76-5
• Molecular Formula: C₂₄H₂₈ClNO₂
• Molecular Weight: 397.94
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: DMSO
• IUPAC Name: (3R)-1-[3-(5,6-dihydrodibenzo[1,2-a:1//',2//'-e][7]annulen-11-ylidene)propyl]piperidine-3-carboxylic acid;hydrochloride
• InChI: InChI=1S/C24H27NO2.ClH/c26-24(27)20-9-5-15-25(17-20)16-6-12-23-21-10-3-1-7-18(21)13-14-19-8-2-4-11-22(19)23;/h1-4,7-8,10-12,20H,5-6,9,13-17H2,(H,26,27);1H/t20-;/m1./s1
• InChIKey: OJCOPCYFLFDPTD-VEIFNGETSA-N
• SMILES: C1CC(CN(C1)CCC=C2C3=CC=CC=C3CCC4=CC=CC=C42)C(=O)O.Cl

ReN-1869 hydrochloride (Cat No.: I013581) is an experimental small molecule under investigation for its potential neurological benefits. Preliminary research suggests it modulates key neurotransmitter systems, thereby offering neuroprotective or behavioral benefits in preclinical models. Through targeted regulation of neural pathways, ReN-1869 hydrochloride may alleviate symptoms in disorders involving abnormal synaptic functioning. Current studies focus on optimizing its pharmacokinetics, assessing safety profiles, and determining efficacy across multiple neurological conditions. If validated, this compound could represent an important addition to the neuropharmacological arsenal of therapies.

Reference

[1]. Olsen UB, et al. ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation. Eur J Pharmacol. 2002 Jan 18;435(1):43-57.