Repaglinide-d5

• CAT Number: S000303
• CAS Number: 1217709-85-7
• Molecular Formula: C27H31D5N2O4
• Molecular Weight: 457.62
• Purity: ≥95%
• IUPAC Name: 4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]-2-(1,1,2,2,2-pentadeuterioethoxy)benzoic acid
• InChI: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1/i1D3,4D2
• InChIKey: FAEKWTJYAYMJKF-NTSVIFQKSA-N
• SMILES: CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O

Repaglinide-d5（Cat No.:S000303） is a deuterated form of repaglinide, where five hydrogen atoms are replaced with deuterium, enhancing its molecular stability. This modification makes it highly useful as an internal standard in analytical methods such as mass spectrometry and NMR spectroscopy. Repaglinide is a meglitinide analog used primarily to manage type 2 diabetes by stimulating insulin secretion from the pancreas. The deuterium in repaglinide-d5 allows for more detailed and precise pharmacokinetic and metabolic studies, enabling researchers to better understand the drug’s behavior in the body, especially its absorption and metabolism.