For research use only. Not for therapeutic Use.
Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug.<br>Reserpine inhibits efflux pumps and reduces sparfloxacin, moxifloxacin and ciprofloxacin IC50s and MICs by up to four-fold in 11, 21 and 48 of the 102 unrelated clinical isolates tested.<br>Reserpine (5 mg/kg s.c.) reduces extracellular DA levels to 4% of basal values in intact rats. Reserpine (5 mg/kg s.c.) diminishes L-DOPA (50 mg/kg i.p.)-induced increases in extracellular dopamine levels to 16% of those obtained in denervated animals not pretreated with reserpine in 6-hydroxydopamine-lesioned rats.
Catalog Number | A000318 |
CAS Number | 50-55-5 |
Synonyms | NA |
Molecular Formula | C33H40N2O9 |
Purity | ≥95% |
Storage | 3 years -20C powder |
InChIKey | QEVHRUUCFGRFIF-MDEJGZGSSA-N |