Resiniferatoxin

• CAT Number: R022222
• CAS Number: 57444-62-9
• Molecular Formula: C37H40O9
• Molecular Weight: 628.70
• Purity: 98%
• Synonyms: RTX; (+)-Resiniferatoxin; [2S-(2α,3aβ,3bβ,6aβ,9aα,9bα,10α,11aβ)]-4-Hydroxy-3-methoxy-, [3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]methyl Es
• Target: TRP Channel
• Solubility: Soluble in DMSO > 10 mM
• Storage: Desiccate at -20C
• Analysis method: HPLC
• IUPAC Name: [(1R,2R,6R,10S,11R,13S,15R,17R)-13-benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-prop-1-en-2-yl-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadeca-3,8-dien-8-yl]methyl 2-(4-hydroxy-3-methoxyphenyl)acetate
• InChI: InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35-,36-,37-/m1/s1
• InChIKey: DSDNAKHZNJAGHN-MXTYGGKSSA-N
• SMILES: CC1CC2(C3C4C1(C5C=C(C(=O)C5(CC(=C4)COC(=O)CC6=CC(=C(C=C6)O)OC)O)C)OC(O3)(O2)CC7=CC=CC=C7)C(=C)C

Resiniferatoxin（Cat No.:R022222）is a high-purity diterpene ester known for its potent analgesic properties, derived from the Euphorbia resinifera plant. It acts as an agonist for the transient receptor potential vanilloid 1 (TRPV1) receptor, which is involved in pain perception. This compound is crucial in neurobiological research for studying pain pathways and developing new pain management therapies. Its intense bioactivity allows for the targeted treatment of chronic pain conditions, making it a valuable tool in pharmacological studies and potential therapeutic applications. Resiniferatoxin is essential for advancing pain research and innovative treatment strategies.