For research use only. Not for therapeutic Use.
Resolvin D2 is a specialized pro-resolving mediator derived from the omega-3 fatty acid, docosahexaenoic acid (DHA). It plays a crucial role in resolving inflammation by stopping the infiltration of neutrophils and stimulating the clearance of inflammatory cells and debris. Resolvin D2 is essential in reducing chronic inflammation and promoting tissue repair. Its application spans various fields, including immunology, cardiovascular research, and therapeutic development for inflammatory diseases. This mediator is pivotal in advancing our understanding of inflammation resolution and holds promise for novel anti-inflammatory treatments and drug development.
| Catalog Number | R016710 |
| CAS Number | 810668-37-2 |
| Synonyms | 7(S),16(R),17(S)-Resolvin D2;RvD2 |
| Molecular Formula | C22H32O5 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | -80°C |
| IUPAC Name | (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid |
| InChI | InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20+,21-/m1/s1 |
| InChIKey | IKFAUGXNBOBQDM-XFMPMKITSA-N |
| SMILES | CC/C=CC[C@H](O)[C@H](O)/C=C/C=C/C=CC=C[C@@H](O)C/C=CCCC(O)=O |
| Reference | 1.Hong, S.,Gronert, K.,Devchand, P.R., et al. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. The Journal of Biological Chemisty 278(17), 14677-14687 |
