For research use only. Not for therapeutic Use.
Resorufin-d6 is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
| Catalog Number | I045502 |
| CAS Number | 1196157-65-9 |
| Synonyms | 1,2,4,6,8,9-hexadeuterio-7-hydroxyphenoxazin-3-one |
| Molecular Formula | C12HD6NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H7NO3/c14-7-1-3-9-11(5-7)16-12-6-8(15)2-4-10(12)13-9/h1-6,14H/i1D,2D,3D,4D,5D,6D |
| InChIKey | HSSLDCABUXLXKM-MZWXYZOWSA-N |
| SMILES | C1=CC2=C(C=C1O)OC3=CC(=O)C=CC3=N2 |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Odyniec ML , et al. ‘AND’-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb). 2018 Jul 26;54(61):8466-8469. |
