Revaprazan Hydrochloride

• CAT Number: R050544
• CAS Number: 178307-42-1
• Molecular Formula: C22H24ClFN4
• Molecular Weight: 398.91
• Purity: ≥95%
• Synonyms: 4-(3,4-Dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-2-pyrimidinamine Hydrochloride; 5,6-Dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-?1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine hydrochloride; Revaprazan Hydrochloride; SB 6
• Target: Immunology/Inflammation
• Storage: -20°C
• IUPAC Name: N-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine;hydrochloride
• InChI: InChI=1S/C22H23FN4.ClH/c1-14-15(2)24-22(25-19-10-8-18(23)9-11-19)26-21(14)27-13-12-17-6-4-5-7-20(17)16(27)3;/h4-11,16H,12-13H2,1-3H3,(H,24,25,26);1H
• InChIKey: MALPZYQJEDBIAK-UHFFFAOYSA-N
• SMILES: CC1C2=CC=CC=C2CCN1C3=NC(=NC(=C3C)C)NC4=CC=C(C=C4)F.Cl

Revaprazan Hydrochloride (Cat No.:R050544) is a novel and potent reversible proton pump inhibitor (PPI) with sustained acid-suppressive effects. It works by inhibiting H(+)/K(+)-ATPase, a proton pump responsible for gastric acid secretion, through reversible binding to the K+ binding site on the pump. This mechanism leads to prolonged reduction of acid production in the stomach, making it an effective treatment for acid-related disorders such as gastroesophageal reflux disease (GERD) and peptic ulcers. As a PPI, Revaprazan Hydrochloride offers extended acid control compared to conventional antacids.