RG7834

• CAT Number: I004342
• CAS Number: 2072057-17-9
• PubChem Substance ID: 118261815
• Molecular Formula: C22H27NO6
• Molecular Weight: 401.50
• Purity: ≥95%
• Synonyms: RG-7834
• Target: HBV
• IUPAC Name: (6S)-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6-propan-2-yl-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid
• InChI: InChI=1S/C22H27NO6/c1-13(2)17-8-14-9-21(29-7-5-6-27-3)20(28-4)10-15(14)18-11-19(24)16(22(25)26)12-23(17)18/h9-13,17H,5-8H2,1-4H3,(H,25,26)/t17-/m0/s1
• InChIKey: KBXLMOYQNDMHQT-KRWDZBQOSA-N
• SMILES: CC(C)[C@@H]1CC2=CC(=C(C=C2C3=CC(=O)C(=CN13)C(=O)O)OC)OCCCOC

RG7834 (Cat No.:I004342), also known as RO7020322, is a novel oral inhibitor of viral gene expression in hepatitis B virus (HBV) infection. It functions by specifically blocking the production of viral antigens and virions. Unlike nucleos(t)ide analogs, RG7834 exhibits a highly selective antiviral activity against HBV. Its unique profile sets it apart as a distinct therapeutic option for HBV infection, with the potential to offer alternative treatment approaches and improved outcomes for patients. Ongoing research and clinical studies aim to further evaluate the efficacy, safety, and potential of RG7834 in the management of HBV infection.

Reference

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