For research use only. Not for therapeutic Use.
RGB-286147（Cat No.:R066926）is a small molecule inhibitor under investigation for its potential in cancer treatment. It selectively targets and inhibits the TANK-binding kinase 1 (TBK1), a key protein involved in inflammatory responses and tumor progression. By inhibiting TBK1, RGB-286147 aims to disrupt cancer cell survival, migration, and inflammation, which are often upregulated in various cancers. This compound shows promise in preclinical studies, particularly in tumors that are resistant to conventional therapies. RGB-286147 is being explored as a potential therapeutic agent for a range of malignancies, including solid tumors and hematologic cancers.
| CAS Number | 784211-09-2 |
| Synonyms | 1-(2,6-dichlorophenyl)-6-[[4-(2-hydroxyethoxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one |
| Molecular Formula | C23H22Cl2N4O3 |
| Purity | ≥95% |
| IUPAC Name | 1-(2,6-dichlorophenyl)-6-[[4-(2-hydroxyethoxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one |
| InChI | InChI=1S/C23H22Cl2N4O3/c1-13(2)20-19-22(29(28-20)21-16(24)4-3-5-17(21)25)26-18(27-23(19)31)12-14-6-8-15(9-7-14)32-11-10-30/h3-9,13,30H,10-12H2,1-2H3,(H,26,27,31) |
| InChIKey | RSQPNXBTPUXMQN-UHFFFAOYSA-N |
| SMILES | CC(C)C1=NN(C2=C1C(=O)NC(=N2)CC3=CC=C(C=C3)OCCO)C4=C(C=CC=C4Cl)Cl |
