Rhein

• CAT Number: I003676
• CAS Number: 478-43-3
• Molecular Formula: C15H8O6
• Molecular Weight: 284.22
• Purity: ≥95%
• Synonyms: NSC 38629;Rheic Acid
• Solubility: 10 mM in DMSO
• Storage: 2-8°C
• IUPAC Name: 4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid
• InChI: InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
• InChIKey: FCDLCPWAQCPTKC-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)C(=O)O

Rhein（Cat No.:I003676） is a lipophilic anthraquinone compound that is commonly found in medicinal herbs. It exhibits a wide range of pharmacological effects, making it a valuable compound in traditional medicine. Rhein has been studied for its hepatoprotective and nephroprotective properties, showing potential benefits for liver and kidney health. Additionally, it possesses anti-inflammatory, antioxidant, anticancer, and antimicrobial activities. These diverse pharmacological effects make rhein a promising candidate for the development of therapeutic interventions in various diseases, including liver and kidney disorders, inflammation-related conditions, cancer, and microbial infections.

Reference

[1]. Yan-Xi Zhou, et al. Rhein: A Review of Pharmacological Activities. Evid Based Complement Alternat Med. 2015; 2015: 578107.

[2]. Xiaowen Chen, et al. Toll-like receptor 4 is involved in a protective effect of rhein on immunoglobulin A nephropathy. Indian J Pharmacol. 2015 Jan-Feb; 47(1): 27–33.

[3]. Hou ML, et al. The Drug-Drug Effects of Rhein on the Pharmacokinetics and Pharmacodynamics of Clozapine in Rat Brain Extracellular Fluid by In Vivo Microdialysis. J Pharmacol Exp Ther. 2015 Oct;355(1):125-34.