RhoNox-1

• CAT Number: I043280
• CAS Number: 1447815-38-4
• Molecular Formula: C28H30N2O4
• Molecular Weight: 458.55
• Purity: ≥95%
• Synonyms: 9-(2-carboxyphenyl)-6-diethylazaniumylidene-N,N-diethylxanthen-3-amine oxide
• IUPAC Name: 2-[3-diethylazaniumylidene-6-[diethyl(oxido)azaniumyl]xanthen-9-yl]benzoate
• InChI: InChI=1S/C28H30N2O4/c1-5-29(6-2)19-13-15-23-25(17-19)34-26-18-20(30(33,7-3)8-4)14-16-24(26)27(23)21-11-9-10-12-22(21)28(31)32/h9-18H,5-8H2,1-4H3
• InChIKey: VBBOPWUGWHUQLA-UHFFFAOYSA-N
• SMILES: CC[N+](=C1C=CC2=C(C3=C(C=C(C=C3)[N+](CC)(CC)[O-])OC2=C1)C4=CC=CC=C4C(=O)[O-])CC

RhoNox-1（Cat No.:I043280）is a selective inhibitor of the Rho GTPase–activating protein (GAP) RhoNox-1, which regulates reactive oxygen species (ROS) production in cells. RhoNox-1 is involved in cellular processes such as inflammation, oxidative stress, and immune response regulation. By inhibiting RhoNox-1, this compound helps reduce ROS generation, which plays a crucial role in diseases like cancer, neurodegenerative disorders, and cardiovascular diseases. RhoNox-1 is used in research to explore the mechanisms of oxidative stress and inflammation and to assess potential therapeutic approaches for diseases linked to excessive ROS production.