Ribocil B

• CAT Number: I013050
• CAS Number: 1825355-55-2
• Molecular Formula: C₁₉H₂₂N₆OS
• Molecular Weight: 382.48
• Purity: ≥95%
• Target: Bacterial
• Solubility: DMSO
• IUPAC Name: 2-[(3S)-1-[[2-(methylamino)pyrimidin-5-yl]methyl]piperidin-3-yl]-6-thiophen-2-yl-1H-pyrimidin-4-one
• InChI: InChI=1S/C19H22N6OS/c1-20-19-21-9-13(10-22-19)11-25-6-2-4-14(12-25)18-23-15(8-17(26)24-18)16-5-3-7-27-16/h3,5,7-10,14H,2,4,6,11-12H2,1H3,(H,20,21,22)(H,23,24,26)/t14-/m0/s1
• InChIKey: ZSXCVAIJFUEGJR-AWEZNQCLSA-N
• SMILES: CNC1=NC=C(C=N1)CN2CCCC(C2)C3=NC(=O)C=C(N3)C4=CC=CS4

Ribocil B（Cat No.:I013050）is a small-molecule inhibitor that targets the FMN riboswitch, a regulatory RNA element controlling riboflavin biosynthesis in bacteria. By binding to the riboswitch, Ribocil B disrupts the production of essential metabolites, ultimately inhibiting bacterial growth. Its unique mechanism offers a novel approach to antibacterial therapy, as it bypasses traditional protein targets and reduces the likelihood of cross-resistance with other antibiotics. Ribocil B is valuable in research focused on RNA-targeted drug development, particularly for combating drug-resistant bacterial infections and exploring new antibiotic pathways.