Ribonulease T1, Aspergillus oryzae

• CAT Number: I041921
• CAS Number: 9026-12-4
• Purity: ≥95%

Ribonulease T1, Aspergillus oryzae (Rnase T1), is commonly used in biochemical research. Ribonuclease T1 is an endonuclease that can specifically degrade single stranded RNA. Ribonuclease T1 can form nucleoside 2 ‘, 3 ‘-cyclic phosphoric acid intermediates to cut the phosphodiester bond between 3’ -guanosine residues and adjacent nucleoside 5 ‘-OH groups to produce 3’ -GMP terminal oligonucleotides[1].

Reference

[1]. Heinemann U, et al. Crystallographic study of mechanism of ribonuclease T1-catalysed specific RNA hydrolysis. J Biomol Struct Dyn. 1983 Oct;1(2):523-38.
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