For research use only. Not for therapeutic Use.
Rifalazil（Cat No.:M105696）is a synthetic antibiotic belonging to the rifamycin class, similar to rifampin, and is known for its broad-spectrum activity against Gram-positive and Gram-negative bacteria, including Mycobacterium species. It works by inhibiting bacterial RNA polymerase, blocking transcription and preventing bacterial replication. Rifalazil has been investigated for treating infections like tuberculosis and other mycobacterial diseases, as well as certain parasitic infections. It has shown promise due to its potent antibacterial effects and favorable pharmacokinetic properties. However, its clinical development has been limited, and it is still under investigation for potential use in antimicrobial therapies.
| Catalog Number | M105696 |
| CAS Number | 129791-92-0 |
| Molecular Formula | C51H64N4O13 |
| Purity | ≥95% |
| Target | Anti-infection |
| Storage | Store at RT |
| IUPAC Name | [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,6,15,17-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30-[4-(2-methylpropyl)piperazin-1-yl]-23,32,37-trioxo-8,27,38-trioxa-24,34-diazahexacyclo[23.11.1.14,7.05,36.026,35.028,33]octatriaconta-1,3,5,9,19,21,25,28,30,33,35-undecaen-13-yl] acetate |
| InChI | InChI=1S/C51H64N4O13/c1-24(2)23-54-16-18-55(19-17-54)32-21-33(57)39-35(22-32)67-48-40(52-39)36-37-44(60)30(8)47-38(36)49(62)51(10,68-47)65-20-15-34(64-11)27(5)46(66-31(9)56)29(7)43(59)28(6)42(58)25(3)13-12-14-26(4)50(63)53-41(48)45(37)61/h12-15,20-22,24-25,27-29,34,42-43,46,58-60,62H,16-19,23H2,1-11H3,(H,53,63)/b13-12+,20-15+,26-14-/t25-,27+,28+,29+,34-,42-,43+,46+,51-/m0/s1 |
| InChIKey | IXSVOCGZBUJEPI-HTQYORAHSA-N |
| SMILES | C[C@H]1/C=C/C=C(\C(=O)NC2=C3C(=C4C(=C(C(=C5C4=C([C@](O5)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)O)C)O)C2=O)N=C6C(=CC(=CC6=O)N7CCN(CC7)CC(C)C)O3)/C |
