Rilmenidine Hemifumarate

• CAT Number: R033220
• CAS Number: 207572-68-7
• Molecular Formula: C24H36N4O6
• Molecular Weight: 476.57
• Purity: ≥95%
• Synonyms: N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine, (E)-2-Butenedioate
• Target: Adrenergic Receptor
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: (E)-but-2-enedioic acid;N-(dicyclopropylmethyl)-4,5-dihydro-1,3-oxazol-2-amine
• InChI: InChI=1S/2C10H16N2O.C4H4O4/c2*1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10;5-3(6)1-2-4(7)8/h2*7-9H,1-6H2,(H,11,12);1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChIKey: LZFATBMLSYHRTC-WXXKFALUSA-N
• SMILES: C1CC1C(C2CC2)NC3=NCCO3.C1CC1C(C2CC2)NC3=NCCO3.C(=CC(=O)O)C(=O)O

Rilmenidine hemifumarate（Cat No.:R033220） is a novel antihypertensive drug that acts as a selective agonist of the I1 imidazoline receptor and alpha2 adrenoceptor. By stimulating these receptors, it exerts its antihypertensive effects. Additionally, rilmenidine hemifumarate has been found to induce autophagy, a cellular process involved in the degradation and recycling of cellular components. The induction of autophagy by rilmenidine hemifumarate may have implications for its therapeutic potential beyond its antihypertensive effects, particularly in conditions where autophagy modulation is desired.