Rimantadine hydrochloride

• CAT Number: I001856
• CAS Number: 1501-84-4
• Molecular Formula: C12H22ClN
• Molecular Weight: 215.76
• Purity: ≥95%
• Synonyms: (R)-1-((1s,3R,5S,7S)-adamantan-1-yl)ethanamine hydrochloride
• Target: Influenza Virus
• Solubility: DMSO: ≥ 2.5 mg/mL
• Storage: Store at -20C
• IUPAC Name: 1-(1-adamantyl)ethanamine;hydrochloride
• InChI: InChI=1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H
• InChIKey: OZBDFBJXRJWNAV-UHFFFAOYSA-N
• SMILES: CC(C12CC3CC(C1)CC(C3)C2)N.Cl

Rimantadine Hydrochloride（Cat No.:I001856）is an antiviral medication primarily used to prevent and treat influenza A infections. By inhibiting the viral M2 protein, rimantadine blocks viral uncoating and replication within host cells, effectively reducing viral spread and symptoms. It is often administered during flu outbreaks or as a preventive measure in high-risk populations. Rimantadine hydrochloride is known for its favorable pharmacokinetics, offering fewer central nervous system side effects compared to similar antivirals. Although effective, its use has diminished with the rise of resistant influenza strains, making it most valuable in targeted applications.

Reference

[1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78.
[2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82.