For research use only. Not for therapeutic Use.
Rineterkib (Cat.No:I019445) is an orally active RAF and ERK1/2 inhibitor in the study of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer.
| Catalog Number | I019445 |
| CAS Number | 1715025-32-3 |
| Molecular Formula | C₂₆H₂₇BrF₃N₅O₂ |
| Purity | ≥95% |
| Reference | [1]. CAPONIGRO, et al. THERAPEUTIC COMBINATIONS COMPRISING A RAF INHIBITOR AND A ERK INHIBITOR. WO2018051306A1. |
