RIPK-IN-4

• CAT Number: I018511
• CAS Number: 2141969-56-2
• Molecular Formula: C₁₈H₂₁FN₄O₃S
• Molecular Weight: 392.45
• Purity: ≥95%
• Target: RIP kinase
• Storage: Store at -20°C
• IUPAC Name: 4-(6-tert-butylsulfonyl-7-ethoxyimidazo[1,2-a]pyridin-3-yl)-6-fluoropyridin-2-amine
• InChI: InChI=1S/C18H21FN4O3S/c1-5-26-13-8-17-21-9-12(11-6-15(19)22-16(20)7-11)23(17)10-14(13)27(24,25)18(2,3)4/h6-10H,5H2,1-4H3,(H2,20,22)
• InChIKey: QWDMZDSZMVJFFJ-UHFFFAOYSA-N
• SMILES: CCOC1=CC2=NC=C(N2C=C1S(=O)(=O)C(C)(C)C)C3=CC(=NC(=C3)F)N

RIPK-IN-4 ( Cat No. : I018511 ) is a selective inhibitor of receptor-interacting protein kinase 1 (RIPK1), a key regulator in cell death pathways, including necroptosis and inflammation. RIPK1 plays a critical role in the inflammatory response and immune system regulation. By inhibiting RIPK1, RIPK-IN-4 helps prevent excessive inflammation and tissue damage, making it a promising candidate for treating inflammatory diseases, neurodegenerative disorders, and certain types of cancer. Its potential therapeutic applications are being explored in preclinical studies for conditions where necroptosis and inflammation contribute to disease progression.