For research use only. Not for therapeutic Use.
RIPK-IN-4 ( Cat No. : I018511 ) is an effective and selective RIPK2 inhibitor with good oral bioavailability with an IC50 value of 3 nM. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.
| Catalog Number | I018511 |
| CAS Number | 2141969-56-2 |
| Molecular Formula | C₁₈H₂₁FN₄O₃S |
| Purity | ≥95% |
| Target | RIP kinase |
| Storage | Store at -20°C |
| IUPAC Name | 4-(6-tert-butylsulfonyl-7-ethoxyimidazo[1,2-a]pyridin-3-yl)-6-fluoropyridin-2-amine |
| InChI | InChI=1S/C18H21FN4O3S/c1-5-26-13-8-17-21-9-12(11-6-15(19)22-16(20)7-11)23(17)10-14(13)27(24,25)18(2,3)4/h6-10H,5H2,1-4H3,(H2,20,22) |
| InChIKey | QWDMZDSZMVJFFJ-UHFFFAOYSA-N |
| SMILES | CCOC1=CC2=NC=C(N2C=C1S(=O)(=O)C(C)(C)C)C3=CC(=NC(=C3)F)N |
| Reference | [1]. He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053. |
