RIPK1-IN-7

For research use only. Not for therapeutic Use.

  • CAT Number: I019038
  • CAS Number: 2300982-44-7
  • Molecular Formula: C₂₅H₂₂F₃N₅O₂
  • Molecular Weight: 481.47
  • Purity: ≥95%
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RIPK1-IN-7 (Cat.No:I019038) is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.


Catalog Number I019038
CAS Number 2300982-44-7
Molecular Formula C₂₅H₂₂F₃N₅O₂
Purity ≥95%
Target RIP kinase
Reference

[1]. Li Y, et al. Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model. J Med Chem. 2018 Dec 27;61(24):11398-11414.

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