Ritonavir-d6

• CAT Number: R003907
• CAS Number: 1217720-20-1
• Molecular Formula: CHDNOS
• Molecular Weight: 726.98
• Purity: ≥95%
• Synonyms: (3S,4S,6S,9S)-4-Hydroxy-12-methyl-9-(1-methylethyl-d6)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-thiazolylmethyl Ester; A 84538-d6; ABT 538-d6; Norvir-d6
• Storage: Store at RT
• IUPAC Name: 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-5-[[(2S)-2-[[[2-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-1,3-thiazol-4-yl]methyl-methylcarbamoyl]amino]-3-methylbutanoyl]amino]-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate
• InChI: InChI=1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1/i3D3,4D3
• InChIKey: NCDNCNXCDXHOMX-GMBJSHJASA-N
• SMILES: [2H]C([2H])([2H])C(C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O)C([2H])([2H])[2H]

Ritonavir-d6（Cat No.:R003907） is a highly specialized deuterated form of the antiretroviral medication Ritonavir, featuring six deuterium atoms. This isotopic modification enhances molecular stability and provides a marked increase in detection sensitivity during mass spectrometry analyses. Primarily used in pharmacokinetic studies, Ritonavir-d6 is essential for understanding drug metabolism and disposition in the human body. Its use facilitates more accurate assessments of the pharmacological properties of Ritonavir, contributing significantly to research in HIV treatment and the development of effective antiretroviral therapies.