Rivaroxaban-d4

• CAT Number: R011673
• CAS Number: 1132681-38-9
• Molecular Formula: C19H18ClN3O5S
• Molecular Weight: 439.903
• Purity: ≥95%
• Synonyms: 5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide; BAY 59-7939-d4
• Target: Factor Xa
• Storage: 2°C to 8°C
• Related CAS: 366789-08-8 (unlabeled)
• IUPAC Name: 5-chloro-N-[[(5S)-2-oxo-3-[2,3,5,6-tetradeuterio-4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
• InChI: InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1/i1D,2D,3D,4D
• InChIKey: KGFYHTZWPPHNLQ-UJCPGTITSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1N2CCOCC2=O)[2H])[2H])N3C[C@@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl)[2H]

Rivaroxaban-d4 is a deuterated form of rivaroxaban, a widely used anticoagulant that functions as a direct factor Xa inhibitor. This compound is labeled with four deuterium atoms, enhancing its stability and making it particularly valuable for pharmacokinetic studies, drug metabolism research, and isotope-dilution mass spectrometry. Rivaroxaban-d4 is essential for investigating the absorption, distribution, metabolism, and excretion (ADME) of rivaroxaban in biological systems. It is also used as a reliable internal standard in analytical chemistry, ensuring precise and reproducible results in the study and development of anticoagulant therapies, particularly in understanding the pharmacokinetics and safety profiles of rivaroxaban.