For research use only. Not for therapeutic Use.
RJR-2403 Oxalate(CAT: I002689) is a selective agonist of the α4β2 nicotinic acetylcholine receptor (nAChR), widely used in neurological research. Its high specificity makes it an essential tool for studying the role of nAChRs in cognitive function, neuroprotection, and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Researchers leverage RJR-2403 Oxalate to investigate therapeutic strategies targeting nicotinic receptors to enhance memory, attention, and overall neural signaling. Its well-characterized pharmacological profile supports its application in preclinical studies, offering valuable insights into cholinergic system modulation and related therapeutic interventions.
| Catalog Number | I002689 |
| CAS Number | 220662-95-3 |
| Synonyms | (E)-N-methyl-4-pyridin-3-ylbut-3-en-1-amine;oxalic acid |
| Molecular Formula | C12H16N2O4 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | 10 mM in H2O |
| Storage | Store at -20°C |
| IC50 | 26 nM [1] |
| IUPAC Name | (E)-N-methyl-4-pyridin-3-ylbut-3-en-1-amine;oxalic acid |
| InChI | InChI=1S/C10H14N2.C2H2O4/c1-11-7-3-2-5-10-6-4-8-12-9-10;3-1(4)2(5)6/h2,4-6,8-9,11H,3,7H2,1H3;(H,3,4)(H,5,6)/b5-2+; |
| InChIKey | WTIZFOAIQXMQHC-DPZBITMOSA-N |
| SMILES | CNCC/C=C/C1=CN=CC=C1.C(=O)(C(=O)O)O |
