Ro 10-5824 dihydrochloride

• CAT Number: I010540
• CAS Number: 189744-94-3
• Molecular Formula: C17H22Cl2N4
• Molecular Weight: 353.291
• Purity: ≥95%
• Synonyms: 5-[(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl-4-pyrimidinamine dihydrochloride
• Target: Dopamine Receptor
• Solubility: Soluble to 100 mM in water and to 75 mM in DMSO
• Storage: Desiccate at RT
• IUPAC Name: 2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine;dihydrochloride
• InChI: InChI=1S/C17H20N4.2ClH/c1-13-19-11-16(17(18)20-13)12-21-9-7-15(8-10-21)14-5-3-2-4-6-14;;/h2-7,11H,8-10,12H2,1H3,(H2,18,19,20);2*1H
• InChIKey: UZHMRJRDYCRKIZ-UHFFFAOYSA-N
• SMILES: CC1=NC=C(C(=N1)N)CN2CCC(=CC2)C3=CC=CC=C3.Cl.Cl

Ro 10-5824 dihydrochloride (Cat.No:I010540) is a chemical compound that acts as a selective positive allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR). It has shown potential in preclinical studies for its cognitive-enhancing effects and neuroprotective properties. Ro 10-5824 dihydrochloride may have therapeutic applications in neurodegenerative disorders like Alzheimer’s disease.