RO-1138452

• CAT Number: I009073
• CAS Number: 221529-58-4
• Molecular Formula: C19H23N3O
• Molecular Weight: 309.413
• Purity: ≥95%
• Synonyms: RO-1138452; RO1138452; RO 1138452.;N-(4-(4-isopropoxybenzyl)phenyl)-4,5-dihydro-1H-imidazol-2-amine4,5-Dihydro-N-(4-((4-(1-methylethoxy)phenyl)methyl)phenyl)-1H-imadazol-2-amine
• Target: Prostaglandin Receptor
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: N-[4-[(4-propan-2-yloxyphenyl)methyl]phenyl]-4,5-dihydro-1H-imidazol-2-amine
• InChI: InChI=1S/C19H23N3O/c1-14(2)23-18-9-5-16(6-10-18)13-15-3-7-17(8-4-15)22-19-20-11-12-21-19/h3-10,14H,11-13H2,1-2H3,(H2,20,21,22)
• InChIKey: GYYRMJMXXLJZAB-UHFFFAOYSA-N
• SMILES: CC(C)OC1=CC=C(C=C1)CC2=CC=C(C=C2)NC3=NCCN3

RO-1138452 (CAT: I009073) is a potent and selective inhibitor of the phosphoinositide 3-kinase (PI3K) delta isoform. This compound interferes with the PI3K signaling pathway, which plays a pivotal role in regulating cell growth, survival, and proliferation. By selectively inhibiting the delta isoform of PI3K, RO-1138452 offers potential for targeted therapeutic interventions in conditions where PI3K signaling is dysregulated, such as certain types of cancer and immune-related disorders.