RO 116 1148

• CAT Number: I009074
• CAS Number: 748763-84-0
• Molecular Formula: C19H28N2O3
• Molecular Weight: 332.44
• Purity: ≥95%
• Synonyms: RO 116 1148 ; RO-116-1148; RO 1161148.;N-[(1-butylpiperidin-4-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: N-[(1-butylpiperidin-4-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
• InChI: InChI=1S/C19H28N2O3/c1-2-3-9-21-10-7-15(8-11-21)14-20-19(22)16-5-4-6-17-18(16)24-13-12-23-17/h4-6,15H,2-3,7-14H2,1H3,(H,20,22)
• InChIKey: VBFBEYXWJLASJA-UHFFFAOYSA-N
• SMILES: O=C(C1=C2OCCOC2=CC=C1)NCC3CCN(CCCC)CC3

RO 116 1148(CAT: I009074) is a potent and selective antagonist of the prostaglandin D2 (PGD2) receptor DP1, widely utilized in immunology and inflammation research. By blocking DP1 receptor activation, it inhibits the effects of PGD2, which is involved in allergic responses, inflammation, and sleep regulation. Researchers use RO 116 1148 to study conditions such as asthma, allergic rhinitis, and other inflammatory diseases. Its high specificity and efficacy make it a valuable tool for investigating the role of PGD2 signaling in pathological processes and developing targeted therapeutic strategies.