Ro 41-0960

• CAT Number: I044115
• CAS Number: 125628-97-9
• Molecular Formula: C13H8FNO5
• Molecular Weight: 277.20
• Purity: ≥95%
• Synonyms: (3,4-dihydroxy-5-nitrophenyl)-(2-fluorophenyl)methanone
• InChI: InChI=1S/C13H8FNO5/c14-9-4-2-1-3-8(9)12(17)7-5-10(15(19)20)13(18)11(16)6-7/h1-6,16,18H
• InChIKey: RQPAUNZYTYHKHA-UHFFFAOYSA-N
• SMILES: C1=CC=C(C(=C1)C(=O)C2=CC(=C(C(=C2)O)O)[N+](=O)[O-])F

Ro 41-0960 is a selective catechol-O-methyltransferase(COMT) inhibitor[1].

Reference

[1]. Storch A, et al. Catechol-O-methyltransferase inhibition attenuates levodopa toxicity in mesencephalic dopamine neurons. Mol Pharmacol. 2000 Mar;57(3):589-94.
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