Ro 48-8071 fumarate

• CAT Number: I009156
• CAS Number: 189197-69-1(fumarate)
• Molecular Formula: C27H31BrFNO6
• Molecular Weight: 564.45
• Purity: ≥95%
• Target: OSC inhibitor
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: (4-bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone;(E)-but-2-enedioic acid
• InChI: InChI=1S/C23H27BrFNO2.C4H4O4/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18;5-3(6)1-2-4(7)8/h3,8-13,17H,1,4-7,14-16H2,2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
• InChIKey: XCYAYLWZCRGKDS-WLHGVMLRSA-N
• SMILES: CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C.C(=C/C(=O)O)\C(=O)O

Ro 48-8071 fumarate（Cat No.:I009156）is a potent and selective inhibitor of the protein kinase C (PKC) family, specifically targeting PKCβ. PKCβ is involved in various cellular processes, including cell growth, differentiation, and immune responses. By inhibiting PKCβ, Ro 48-8071 fumarate has shown potential in modulating inflammatory and immune-related diseases, as well as certain cancers. It has been investigated for its therapeutic applications in conditions such as autoimmune disorders and inflammatory diseases. However, further research and clinical trials are required to fully establish its safety, efficacy, and long-term benefits in human treatments.