RO-61-0593

• CAT Number: I009167
• CAS Number: 186423-40-5
• Molecular Formula: C14H24O5
• Molecular Weight: 272.34
• Purity: ≥95%
• Synonyms: RO-61-0593; RO 610593; RO 61-0593.;2-Furanbutanoic acid, alpha-hexyltetrahydro-beta-hydroxy-5-oxo-
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: (2S)-2-[(1R)-1-hydroxy-2-[(2S)-5-oxooxolan-2-yl]ethyl]octanoic acid
• InChI: InChI=1S/C14H24O5/c1-2-3-4-5-6-11(14(17)18)12(15)9-10-7-8-13(16)19-10/h10-12,15H,2-9H2,1H3,(H,17,18)/t10-,11-,12+/m0/s1
• InChIKey: NCLNUVSGJFDTNY-SDDRHHMPSA-N
• SMILES: CCCCCCC(C(CC1CCC(=O)O1)O)C(=O)O

RO-61-0593(CAT: I009167) is a selective and potent inhibitor of the T-type calcium channel, widely used in neurophysiological and cardiovascular research. By blocking T-type calcium channel activity, it disrupts calcium influx associated with neuronal excitability, pacemaker activity, and muscle contraction. This compound is particularly valuable for studying conditions such as epilepsy, chronic pain, and cardiovascular arrhythmias. With high specificity and efficacy, RO-61-0593 provides a robust tool for exploring the physiological and pathological roles of T-type calcium channels. Its exceptional stability and purity make it suitable for in vitro and in vivo studies, advancing drug discovery for channelopathies and related disorders.