For research use only. Not for therapeutic Use.
RO0711401 is a novel small-molecule antagonist of the corticotropin-releasing factor receptor 1 (CRF1). It has been explored for its potential in treating anxiety, depression, and stress-related disorders, where dysregulation of the CRF system plays a key role. By blocking CRF1 receptors, RO0711401 reduces the stress response and associated behaviors, offering a targeted approach to managing conditions exacerbated by chronic stress. Research on RO0711401 focuses on its efficacy, safety, and potential as a therapeutic agent in neuropsychiatric disorders.
| Catalog Number | I009064 |
| CAS Number | 714971-87-6 |
| Synonyms | N-[4-(trifluoromethyl)-1,3-oxazol-2-yl]-9H-xanthene-9-carboxamide |
| Molecular Formula | C18H11F3N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H11F3N2O3/c19-18(20,21)14-9-25-17(22-14)23-16(24)15-10-5-1-3-7-12(10)26-13-8-4-2-6-11(13)15/h1-9,15H,(H,22,23,24) |
| InChIKey | GSGDLBUOSWGZER-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C3O2)C(=O)NC4=NC(=CO4)C(F)(F)F |
