For research use only. Not for therapeutic Use.
RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase)[1].
| Catalog Number | M142841 |
| CAS Number | 1258296-60-4 |
| Synonyms | N-[2-[(2-amino-6-methylpyrimidin-4-yl)amino]pyridin-4-yl]-2,6-dichlorobenzamide |
| Molecular Formula | C17H14Cl2N6O |
| Purity | ≥95% |
| InChI | InChI=1S/C17H14Cl2N6O/c1-9-7-14(25-17(20)22-9)24-13-8-10(5-6-21-13)23-16(26)15-11(18)3-2-4-12(15)19/h2-8H,1H3,(H4,20,21,22,23,24,25,26) |
| InChIKey | LNGDQKGREFSTHB-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NC(=N1)N)NC2=NC=CC(=C2)NC(=O)C3=C(C=CC=C3Cl)Cl |
| Reference | [1]. Tobie D. Lee, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology November 2019, 96 (5) 629-640. |
