For research use only. Not for therapeutic Use.
ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research[1].
| Catalog Number | I041722 |
| CAS Number | 692870-25-0 |
| Synonyms | 2-(2-chloro-6-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide |
| Molecular Formula | C16H11ClFN3OS |
| Purity | ≥95% |
| InChI | InChI=1S/C16H11ClFN3OS/c17-12-2-1-3-13(18)11(12)8-15(22)21-16-20-14(9-23-16)10-4-6-19-7-5-10/h1-7,9H,8H2,(H,20,21,22) |
| InChIKey | BPGUVXHQHDKSTA-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)Cl)CC(=O)NC2=NC(=CS2)C3=CC=NC=C3)F |
| Reference | [1]. Jingrong Cao, et al. Compositions useful as inhibitors of rock and other protein kinases. WO2004041813A1. |
