ROCK1-IN-1

• CAT Number: I043159
• CAS Number: 692869-38-8
• Molecular Formula: C17H15N3O2S
• Molecular Weight: 325.38
• Purity: ≥95%
• Synonyms: 2-(4-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide
• InChI: InChI=1S/C17H15N3O2S/c1-22-14-4-2-12(3-5-14)10-16(21)20-17-19-15(11-23-17)13-6-8-18-9-7-13/h2-9,11H,10H2,1H3,(H,19,20,21)
• InChIKey: ALHMHPNOEONPMW-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)CC(=O)NC2=NC(=CS2)C3=CC=NC=C3

ROCK1-IN-1 is a ROCK1 inhibitor with a Ki value of 540 nM. ROCK1-IN-1 can be used for the research of hypertension, glaucoma and erectile dysfunction[1].

Reference

[1]. Green J, et al. Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors. J Med Chem. 2015 Jun 25;58(12):5028-37.
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