Rocuronium

• CAT Number: I001683
• CAS Number: 143558-00-3
• Molecular Formula: C32H53N2O4+
• Molecular Weight: 529.786
• Purity: ≥95%
• Synonyms: 1-(17-acetoxy-3-hydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium
• Target: AChR
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
• InChI: InChI=1S/C32H53N2O4/c1-5-14-34(15-6-7-16-34)28-20-26-24-9-8-23-19-29(36)27(33-12-17-37-18-13-33)21-32(23,4)25(24)10-11-31(26,3)30(28)38-22(2)35/h5,23-30,36H,1,6-21H2,2-4H3/q+1/t23-,24+,25-,26-,27-,28-,29-,30-,31-,32-/m0/s1
• InChIKey: YXRDKMPIGHSVRX-OOJCLDBCSA-N
• SMILES: CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C

Rocuronium (Cat.No:I001683) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.

Reference

[1]. Konishi J, Suzuki T, Kondo Y, Baba M, Ogawa S.
Rocuronium and sugammadex used effectively for electroconvulsive therapy in a patient with Brugada syndrome.
J ECT. 2012 Jun;28(2):e21-2.

[2]. Zhang Y, Xiang Y, Liu J.
Prevention of pain on injection of rocuronium: a comparison of lidocaine with different doses of parecoxib.
J Clin Anesth. 2012 Jul 2.

[3]. Suzuki T, Nameki K, Shimizu H, Shimizu Y, Nakamura R, Ogawa S.
Efficacy of rocuronium and sugammadex in a patient with dermatomyositis.
Br J Anaesth. 2012 Apr;108(4):703.

[4]. Illodo Miramontes G, Doniz Campos M, Filgueira Garrido P, Vázquez Martínez A.
Rocuronium used in rapid sequence intubation and reversal with sugammadex in a patient with myasthenia gravis.Rev Esp Anestesiol Reanim. 2011 Dec;58(10):626-7.

[5]. García Sánchez JI, Martínez Hurtado ED, Tordecilla Echenique YY, Santa-Ursula TJ.
Rocuronium used after sugammadex.Rev Esp Anestesiol Reanim. 2011 Dec;58(10):620-1.