For research use only. Not for therapeutic Use.
Roemerine, an aporphine alkaloid, isolated from the leaves of Fibraurea recisa Pierre, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1].
| Catalog Number | I015359 |
| CAS Number | 548-08-3 |
| Synonyms | (12R)-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaene |
| Molecular Formula | C18H17NO2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3/t14-/m1/s1 |
| InChIKey | JCTYWRARKVGOBK-CQSZACIVSA-N |
| SMILES | CN1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3 |
| Reference | [1]. M You, et al. (-)-Roemerine, an Aporphine Alkaloid From Annona Senegalensis That Reverses the Multidrug-Resistance Phenotype With Cultured Cells. J Nat Prod. 1995 Apr;58(4):598-604. |
