For research use only. Not for therapeutic Use.
Ropinirole a selective dopamine D2 receptors agonist with K<sub>i</sub> of 29 nM.<br>Ropinirole scavenges free radicals and suppresses lipid peroxidation in the Fe<br>Ropinirole (50 mg/kg, i.p.) causes biphasic spontaneous locomotor activity in mice. Ropinirole (0.05-1.0 mg/kg SC) dose-dependently inhibits the dyskinesias induced by 2-di-n-propylamino-5,6-di-hydroxytetralin in mice. Ropirtirole, at doses of 1 and 10 μg, injected unilaterally directly into the striatum of the rat causes marked, contralateral (away from the side of injection) asymmetry and circling in mice. Ropinirole (0.05-1.0 mg/kg SC or 0.1 mg/kg PO) reverses all motor and behavioural deficits induced by MPTP in marmosets.
| Catalog Number | A001191 |
| CAS Number | 91374-20-8 |
| Synonyms | KF-101468A |
| Molecular Formula | C16H24N2O.HCl |
| Purity | ≥95% |
| Target | D2 receptor |
| Storage | 3 years -20C powder |
