ROS kinases-IN-1

• CAT Number: I042643
• CAS Number: 370096-57-4
• Molecular Formula: C20H16N4O
• Molecular Weight: 328.37
• Purity: ≥95%
• Synonyms: (4E)-4-[(1,3-diphenylpyrazol-4-yl)methylidene]-3-methyl-1H-pyrazol-5-one
• IUPAC Name: (4Z)-4-[(1,3-diphenylpyrazol-4-yl)methylidene]-3-methyl-1H-pyrazol-5-one
• InChI: InChI=1S/C20H16N4O/c1-14-18(20(25)22-21-14)12-16-13-24(17-10-6-3-7-11-17)23-19(16)15-8-4-2-5-9-15/h2-13H,1H3,(H,22,25)/b18-12-
• InChIKey: DGSFFYVACCJJGR-PDGQHHTCSA-N
• SMILES: CC\1=NNC(=O)/C1=C\C2=CN(N=C2C3=CC=CC=C3)C4=CC=CC=C4

ROS kinases-IN-1（Cat No.:I042643）is a small molecule inhibitor targeting receptor tyrosine kinases in the ROS (Rearranged during Transfection) family, which play a critical role in cellular processes like growth, differentiation, and survival. Dysregulated ROS kinases have been linked to various cancers, particularly in lung, breast, and brain tumors. By inhibiting these kinases, ROS kinases-IN-1 aims to prevent tumor cell proliferation and metastasis, making it a potential therapeutic candidate for treating cancers that involve ROS kinase activation. Currently, it is undergoing preclinical research to assess its safety, efficacy, and therapeutic potential in oncology.