For research use only. Not for therapeutic Use.
Rosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice [1].
Rosarin (0-50 μg/ml; 18 hours) pretreats 30 mins in LPS-induced BV-2 cells supresses iNOS and cytokines expression in a concentration-dependent manner in the murine BV2 cells[1].
| Catalog Number | R072704 |
| CAS Number | 84954-93-8 |
| Synonyms | (2R,3S,4S,5R,6R)-2-[[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol |
| Molecular Formula | C20H28O10 |
| Purity | ≥95% |
| InChI | InChI=1S/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1 |
| InChIKey | IEBFEMIXXHIISM-YZOUKVLTSA-N |
| SMILES | C1=CC=C(C=C1)C=CCOC2C(C(C(C(O2)COC3C(C(C(O3)CO)O)O)O)O)O |
| Reference | [1]. Lee Y, et al. Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.Evid Based Complement Alternat Med. 2013;2013:514049. |
