For research use only. Not for therapeutic Use.
Rosiptor (formerly AQX-1125) is a small-molecule activator of the SH2-containing inositol phosphatase 1 (SHIP1) pathway, primarily studied for its anti-inflammatory effects. By modulating SHIP1 activity, rosiptor helps regulate immune responses, reducing inflammation and immune cell activation. It has been investigated for the treatment of conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic obstructive pulmonary disease (COPD). Rosiptor’s ability to dampen inflammatory signaling without broadly suppressing the immune system makes it a promising therapeutic candidate for chronic inflammatory diseases, potentially offering symptom relief with a favorable safety profile.
| Catalog Number | I008865 |
| CAS Number | 782487-28-9 |
| Synonyms | (1S,3S,4R)-4-[(3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methylidene-3,3a,4,5,6,7-hexahydro-2H-inden-5-yl]-3-(hydroxymethyl)-4-methylcyclohexan-1-ol |
| Molecular Formula | C20H35NO2 |
| Purity | ≥95% |
| InChI | InChI=1S/C20H35NO2/c1-13-4-5-17-16(11-21)18(7-9-19(13,17)2)20(3)8-6-15(23)10-14(20)12-22/h14-18,22-23H,1,4-12,21H2,2-3H3/t14-,15+,16+,17+,18+,19-,20+/m1/s1 |
| InChIKey | MDEJTPWQNNMAQF-BVMLLJBZSA-N |
| SMILES | CC1(CCC(CC1CO)O)C2CCC3(C(C2CN)CCC3=C)C |
