Rosmarinic acid

For research use only. Not for therapeutic Use.

  • CAT Number: I002562
  • CAS Number: 20283-92-5
  • Molecular Formula: C18H16O8
  • Molecular Weight: 360.3
  • Purity: ≥95%
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Rosmarinic acid(Cat No.:I002562) is a naturally-occurring polyphenol known for its antioxidative and anti-inflammatory properties. It exhibits potent antioxidant effects, found in various herbs, such as rosemary and basil, protecting against oxidative stress-induced damage. Additionally, rosmarinic acid demonstrates anti-inflammatory activity by inhibiting inflammatory mediators and enzymes. Its natural origin, along with its antioxidative and anti-inflammatory properties, positions rosmarinic acid as a promising compound for potential therapeutic applications in various diseases and as a dietary supplement for overall health and well-being.


Catalog Number I002562
CAS Number 20283-92-5
Synonyms

(R)-α-[[3-(3,4-dihydroxyphenyl)-1-oxo-2E-propenyl]oxy]-3,4-dihydroxy-benzenepropanoic acid

Molecular Formula C18H16O8
Purity ≥95%
Solubility DMSO: ≥ 32 mg/mL
Storage 2-8°C
IUPAC Name (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxypropanoic acid
InChI InChI=1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
InChIKey DOUMFZQKYFQNTF-WUTVXBCWSA-N
SMILES C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O
Reference

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<br>[1]. Chiaki Sanbongi, et al. Rosmarinic acid inhibits lung injury induced by diesel exhaust particles. Free Radical Biology and Medicine Volume 34, Issue 8, 15 April 2003, Pages 1060–1069
<br>[2]. Hiroshi Takeda, et al. Rosmarinic acid and caffeic acid produce antidepressive-like effect in the forced swimming test in mice. European Journal of Pharmacology Volume 449, Issue 3, 9 August 2002, Pages 261–267
<br>[3]. Pereira P, et al. Neurobehavioral and genotoxic aspects of rosmarinic acid. Pharmacol Res. 2005 Sep;52(3):199-203.
<br>[4]. Wenqing Xu, et al. Protective effects of rosmarinic acid against radiation-induced damage to the hematopoietic system in mice. J Radiat Res. 2016 Mar 22. pii: rrw021
<br>[5]. Fernando PM, et al. Rosmarinic Acid Attenuates Cell Damage against UVB Radiation-Induced Oxidative Stress via Enhancing Antioxidant Effects in Human HaCaT Cells. Biomol Ther (Seoul). 2016 Jan;24(1):75-84.
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