Rotigotine Hydrochloride

• CAT Number: I001020
• CAS Number: 125572-93-2
• Molecular Formula: C19H26ClNOS
• Molecular Weight: 351.93
• Purity: ≥95%
• Synonyms: (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol;hydrochloride
• Target: Neuronal Signaling
• Solubility: 10 mM in water ; 100 mM in DMSO
• Storage: Store at -20°C
• IC50: 13/0.71 nM (D2/D3) [1]
• InChI: InChI=1S/C19H25NOS.ClH/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21;/h3-7,13,16,21H,2,8-12,14H2,1H3;1H/t16-;/m0./s1
• InChIKey: CEXBONHIOKGWNU-NTISSMGPSA-N
• SMILES: CCCN(CCC1=CC=CS1)[C@H]2CCC3=C(C2)C=CC=C3O.Cl

Rotigotine Hydrochloride(CAT: I001020) is a high-purity dopamine agonist primarily utilized in neurology research. As a selective agonist for D2, D3, and D4 dopamine receptors, it plays a critical role in studying dopaminergic signaling pathways and their implications in neurodegenerative disorders such as Parkinson’s disease and restless legs syndrome. By mimicking dopamine’s action, Rotigotine Hydrochloride aids in investigating motor control, synaptic transmission, and neuroprotective strategies. With exceptional solubility and stability, it is suitable for in vitro and in vivo applications. This compound is essential for advancing drug discovery in neurology and exploring potential therapeutic interventions for dopaminergic dysfunction.