For research use only. Not for therapeutic Use.
This product is a derivative of pure 5-carboxy-ROX.5-Carboxy-X-rhodamine N-succinimidyl ester (ROX-SE) is used as an amine coupling reagent to form 5-carboxy-X-rhodamine (ROX) derivatized compounds such as proteins, nucleic acids and drugs that may be analyzed by fluorescence resonance energy transfer (FRET) and fluorescence quenching applications.Labeling reagent for preparation of charge-modified dye-labeled ddNTPs to "direct-load" DNA sequencing
| Catalog Number | I035713 |
| CAS Number | 209734-74-7 |
| Synonyms | ROX-SE, 5-Carboxy-X-rhodamine N-succinimidyl ester |
| Molecular Formula | C37H33N3O7 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 5-Carboxy-X-rhodamine N-succinimidyl ester |
| InChI | InChI=1S/C37H33N3O7/c41-29-11-12-30(42)40(29)47-37(45)22-9-10-23(26(19-22)36(43)44)31-27-17-20-5-1-13-38-15-3-7-24(32(20)38)34(27)46-35-25-8-4-16-39-14-2-6-21(33(25)39)18-28(31)35/h9-10,17-19H,1-8,11-16H2 |
| InChIKey | BTTBJYLMDASSAS-UHFFFAOYSA-N |
| SMILES | O=C(ON1C(CCC1=O)=O)C2=CC=C(C(C([O-])=O)=C2)C(C3=CC(CCC4)=C(N4CCC5)C5=C3O6)=C(C=C7CCC8)C6=C9C7=[N+]8CCC9 |
| Reference | 1. Konopka, C.J.; Wozniak, M.; Hedhli, J.; Ploska, A.; Schwartz-Duval, A.; Siekierzycka, A.; Pan, D.; Munirathinam, G.; Dobrucki, I.T.; Kalinowski, L.; Dobrucki, L.W. Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles. Theranostics, 2018, 8(18), 5012–5024. doi: 10.7150/thno.24791 |
