For research use only. Not for therapeutic Use.
Rp-8-CPT-cAMP is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs, 8-CPT-cyclic AMP (Item No. <span class=/itemid/>12011</span>) and Rp-cyclic AMPS (Item No. <span class=/itemid/>16985</span>). It functions as a site-selective inhibitor of protein kinase A (PKA) type I and II, with preference towards site A of type I and site B of type II. By occupying cAMP binding sites at the regulatory subunit of PKA, Rp-8-CPT-cAMP prevents the kinase holoenzyme from dissociative activation.
| Catalog Number | R025526 |
| CAS Number | 221905-35-7 |
| Synonyms | Rp-8-CPT-cAMP |
| Molecular Formula | C16H14ClN5O5PS2 • Na |
| Purity | ≥95% |
| Target | TGF-beta/Smad |
| Storage | -20°C |
| InChIKey | AWXMSJRRXLCVMW-ALHPSJIMSA-M |
