For research use only. Not for therapeutic Use.
RPR132595A hydrochloride（Cat No.:I041242）is a potent and selective inhibitor of the enzyme phosphodiesterase 4 (PDE4), which plays a crucial role in the regulation of cyclic AMP (cAMP) levels in cells. By inhibiting PDE4, RPR132595A hydrochloride increases cAMP levels, leading to reduced inflammation and immune response. This compound has been investigated for its potential in treating inflammatory diseases, such as asthma, chronic obstructive pulmonary disease (COPD), and other conditions associated with excessive immune activation. Its targeted mechanism makes it a promising candidate for modulating inflammatory pathways in various therapeutic settings.
| Synonyms | [(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-aminopiperidine-1-carboxylate;hydrochloride |
| Molecular Formula | C28H31ClN4O6 |
| Purity | ≥95% |
| IUPAC Name | [(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-aminopiperidine-1-carboxylate;hydrochloride |
| InChI | InChI=1S/C28H30N4O6.ClH/c1-3-17-18-11-16(38-27(35)31-9-7-15(29)8-10-31)5-6-22(18)30-24-19(17)13-32-23(24)12-21-20(25(32)33)14-37-26(34)28(21,36)4-2;/h5-6,11-12,15,36H,3-4,7-10,13-14,29H2,1-2H3;1H/t28-;/m0./s1 |
| InChIKey | LFDSFKHCCHQHBL-JCOPYZAKSA-N |
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
