RPW-24

• CAT Number: I017910
• CAS Number: 1001625-82-6
• Molecular Formula: C₁₅H₁₃ClN₄
• Molecular Weight: 284.74
• Purity: ≥95%
• Target: Bacterial
• Storage: 2-8°C(protect from light)
• IUPAC Name: 2-N-(3-chloro-4-methylphenyl)quinazoline-2,4-diamine
• InChI: InChI=1S/C15H13ClN4/c1-9-6-7-10(8-12(9)16)18-15-19-13-5-3-2-4-11(13)14(17)20-15/h2-8H,1H3,(H3,17,18,19,20)
• InChIKey: LFMFPKKYRXFHHZ-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C=C1)NC2=NC3=CC=CC=C3C(=N2)N)Cl

RPW-24（Cat No.:I017910） is a compound that protects Caenorhabditis elegans (C. elegans) against bacterial infections. It achieves this by stimulating the innate immune response of the nematode. In addition to its immunomodulatory effects, RPW-24 also exhibits antibacterial activity. This property allows it to directly target and inhibit the growth of bacterial pathogens, thereby enhancing the overall defense mechanisms of C. elegans against microbial invaders. The dual action of RPW-24 in boosting the host immune response and exerting antibacterial effects makes it a promising candidate for further research in combating bacterial infections.

Reference

[1]. Pukkila-Worley R, et al. Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection. PLoS Genet. 2012;8(6):e1002733.