RS 25344

• CAT Number: M132180
• CAS Number: 152814-89-6
• Molecular Formula: C19H13N5O4
• Molecular Weight: 375.34
• Purity: ≥95%
• IUPAC Name: 1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4-dione
• InChI: InChI=1S/C19H13N5O4/c25-18-16-5-2-8-21-17(16)23(14-3-1-4-15(11-14)24(27)28)19(26)22(18)12-13-6-9-20-10-7-13/h1-11H,12H2
• SMILES: C1=CC(=CC(=C1)[N+](=O)[O-])N2C3=C(C=CC=N3)C(=O)N(C2=O)CC4=CC=NC=C4

RS 25344 is a selective phosphodiesterase-4 (PDE4) inhibitor with an IC50 value of 0.28 nM.
KEYWORDS: RS 25344 | Supplier | PDE4 inhibitor | RS25344 | RS-25344 | CAS [152814-89-6] | [152815-28-6] | cAMP | PDE | Inhibitor | Enzymes

Reference

T Kaneko et al. Elevated intracellular cyclic AMP inhibits chemotaxis in human eosinophils. Cell Signal. 1995 Jul;7(5):527-34.