For research use only. Not for therapeutic Use.
RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells[1].
| Catalog Number | R022238 |
| CAS Number | 1418131-46-0 |
| Synonyms | 3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide |
| Molecular Formula | C18H15N3O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H15N3O2/c19-18(23)12-4-3-5-14(10-12)21-17(22)9-8-13-11-20-16-7-2-1-6-15(13)16/h1-11,20H,(H2,19,23)(H,21,22)/b9-8+ |
| InChIKey | HYUDSQGICKAEGE-CMDGGOBGSA-N |
| SMILES | C1=CC=C2C(=C1)C(=CN2)C=CC(=O)NC3=CC=CC(=C3)C(=O)N |
| Reference | [1]. Lee J, et al. A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells. Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12509-1 |
