RSV604 racemate

• CAT Number: I004543
• CAS Number: 676128-62-4
• Molecular Formula: C22H17FN4O2
• Molecular Weight: 388.39
• Purity: ≥95%
• Target: RSV
• Solubility: DMSO
• Storage: Store at -20°C
• IUPAC Name: 1-(2-fluorophenyl)-3-(2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl)urea
• InChI: InChI=1S/C22H17FN4O2/c23-16-11-5-7-13-18(16)25-22(29)27-20-21(28)24-17-12-6-4-10-15(17)19(26-20)14-8-2-1-3-9-14/h1-13,20H,(H,24,28)(H2,25,27,29)
• InChIKey: MTPVBMVUENFFLL-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=NC(C(=O)NC3=CC=CC=C32)NC(=O)NC4=CC=CC=C4F

RSV604 (Cat No.:I004543) racemate refers to a mixture of the enantiomers of RSV604, a compound investigated for its activity against the respiratory syncytial virus (RSV). The racemic mixture, which contains both the R and S isomers, exhibits reduced potency against RSV strains compared to the S-isomer alone. The S-isomer of RSV604 is the more active component, demonstrating greater efficacy in inhibiting RSV replication.

Reference

[1]. 1,4-benzodiazepines as inhibitors of respiratory syncytial virus. The identification of a clinical candidate.
Henderson EA, et al. J Med Chem. 2007 Apr 5;50(7):1685-92.