RSVA 405

• CAT Number: I011111
• CAS Number: 140405-36-3
• Molecular Formula: C17H20N4O2
• Molecular Weight: 312.37
• Purity: ≥95%
• Synonyms: 2-[[4-(Diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid
• Target: AMPK
• Solubility: Soluble to 50 mM in DMSO and to 5 mM in ethanol
• Storage: Store at -20C
• IUPAC Name: N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide
• InChI: InChI=1S/C17H20N4O2/c1-3-21(4-2)15-6-5-14(16(22)11-15)12-19-20-17(23)13-7-9-18-10-8-13/h5-12,22H,3-4H2,1-2H3,(H,20,23)/b19-12+
• InChIKey: GWQPCBPAOAFXSJ-XDHOZWIPSA-N
• SMILES: CCN(CC)C1=CC(=C(C=C1)/C=N/NC(=O)C2=CC=NC=C2)O

RSVA 405（Cat No.:I011111）is a selective inhibitor of the protein kinase AMP-activated protein kinase (AMPK), known for its role in regulating cellular energy homeostasis. By inhibiting AMPK, RSVA 405 modulates metabolic pathways related to glucose and lipid metabolism, making it a valuable tool in research focused on metabolic disorders, obesity, and cancer. This compound has shown potential in preclinical studies, particularly in exploring its effects on cell proliferation and survival. RSVA 405’s ability to influence key metabolic processes positions it as a significant candidate for therapeutic development in related diseases.