RTI-336-d3

• CAT Number: R056609
• CAS Number: NA
• Molecular Formula: C₂₄H₂₃D₃Cl₂N₂O
• Molecular Weight: 432.4
• Purity: ≥95%
• Synonyms: (1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-(methyl-d3)-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride; [1R-(exo,exo)]-3-(4-Chlorophenyl)-8-(methyl-d3)-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride; R
• Storage: Store at RT
• IUPAC Name: 5-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-(trideuteriomethyl)-8-azabicyclo[3.2.1]octan-2-yl]-3-(4-methylphenyl)-1,2-oxazole;hydrochloride
• InChI: InChI=1S/C24H25ClN2O.ClH/c1-15-3-5-17(6-4-15)21-14-23(28-26-21)24-20(16-7-9-18(25)10-8-16)13-19-11-12-22(24)27(19)2;/h3-10,14,19-20,22,24H,11-13H2,1-2H3;1H/t19-,20+,22+,24-;/m0./s1/i2D3
• InChIKey: IZMZEMAKFSYLMD-COAUSSQRSA-N
• SMILES: [2H]C([2H])([2H])N1[C@H]2CC[C@@H]1[C@H]([C@H](C2)C3=CC=C(C=C3)Cl)C4=CC(=NO4)C5=CC=C(C=C5)C.Cl

RTI-336-d3 is a deuterated analog of RTI-336, a compound known for its role as a dopamine transporter inhibitor. Featuring three deuterium atoms, this isotopically labeled version is essential for advanced research in neuropharmacology, particularly in the study of dopamine-related disorders such as addiction and Parkinson’s disease. The deuterium labeling allows for precise tracking in pharmacokinetic and metabolic studies using mass spectrometry, providing enhanced stability and accuracy. RTI-336-d3 is invaluable in the development and testing of therapeutic agents targeting the dopamine system, offering reliable data for understanding drug action and metabolism in the central nervous system.