For research use only. Not for therapeutic Use.
Ruboxistaurin mesylate (Cat.No:I002303) is a kinase inhibitor used in medical research and clinical trials. It targets protein kinase C beta (PKCβ), an enzyme involved in cell signaling pathways. Ruboxistaurin mesylate has shown promise in preclinical studies for its potential applications in the treatment of diabetic retinopathy and diabetic nephropathy.
Catalog Number | I002303 |
CAS Number | 192050-59-2 |
Synonyms | LY 333531 mesylate; Ruboxistaurin mesylate |
Purity | ≥95% |
Target | TGF-beta/Smad |
InChI | 1S/C28H28N4O3.CH4O3S/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;1-5(2,3)4/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H3,(H,2,3,4)/t18-;/m0./s1 |
InChIKey | DUHQBKLTAVUXFF-FERBBOLQSA-N |
SMILES | CN(C)<wbr>C[C@@H]1CCn2cc(c3c2cccc3)<wbr>C4=C(c5cn(c6c5cccc6)<wbr>CCO1)<wbr>C(=O)<wbr>NC4=O.CS(=O)<wbr>(=O)<wbr>O |